504: Maternal inflammation programs fetal renal development
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چکیده
منابع مشابه
Effects of Maternal Renal Dysfunction on Fetal Development
Maternal conditions affect the growth of the fetal kidney, which begins to secrete urine during late gestation (Bakala et al., 1985; Schaeverbeke & Cheignon, 1980). For example, during pregnancy, the maternal kidney undergoes various changes such as an increase in glomerular filtration rate (Baylis, 1994; Atherton & Pirie, 1981) and an alteration in tubular function (Dafnis & Sabatini, 1992). F...
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Rudolf Cardinal, 22/24 Nov 1998 Implantation and the decidual response • Implantation in humans and some other species is invasive – the uterine surface epithelium is breached and the underlying stroma is invaded. (In yet other species, the epithelium remains intact with the fetal and maternal epithelia in close contact.) • The blastocyst makes a signal (unknown) which induces a stromal respons...
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BACKGROUND Chronic inflammatory disorders have been increasing in incidence over the past decades following geographical patterns of industrialization. Fetal exposure to maternal inflammation may alter organ functions and the offspring's disease risk. We studied the development of genetically-driven ileitis and colitis in response to maternal inflammation using mouse models. METHODS Disease s...
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Cholesterol is required for fetal development. Data obtained from recent studies in humans, rodents, and cell cultures showed that circulating maternal cholesterol can affect fetal metabolism and sterol accretion. Recent studies in our laboratory showed that the efflux of cholesterol from the basolateral side of the placental cells and the secretion of cholesterol from endodermal yolk sac cells...
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BACKGROUND Fetal microchimeric cells that have trafficked into the maternal circulation persist in maternal tissues for years after pregnancy, but their biological role is unclear. We investigated whether fetal cells participate in maternal tissue repair during human pregnancy. METHODS Appendix specimens were acquired from women undergoing appendicectomy during (n = 8) or after (n = 1) pregna...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2017
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2016.11.239